Berlinguet J C, Huet M, Cantin M
Pathol Biol (Paris). 1976 Mar;24(3):175-82.
A technique for the autotransplantation of part of the right atrium in the rat kidney is described. The morphology of these grafts has been studied by light and electron microscopy at intervals varying from 15 to 346 days after transplantation. On light microscopy, the grafts show an organoid organization with a central cavity filled with blood surrounded by an endothelium around which concentric layers of cardiocytes are present. Electron microscopy reveals that the population of specific granules is not affected by transplantation. In the beginning, the cardiocytes show severe abnormalities of myofilaments, mitochondria and sarcoplasmic reticulum. The granular sarcoplasmic reticulum is much more abundant than in control cardiocytes. Most of these changes regress with time so that, after 346 days the transplanted cardiocytes appear almost normal. These experiments indicate that the specific granule population of atrial cardiocytes probably does not contain any appreciable amount of catecholamine and is not dependant on the nervous system or on a local stimulus.
本文描述了一种大鼠肾脏内右心房部分自体移植的技术。在移植后15至346天的不同时间间隔，通过光学显微镜和电子显微镜研究了这些移植物的形态。光学显微镜下，移植物呈现类器官组织，中央腔充满血液，周围有内皮，内皮周围存在同心层的心肌细胞。电子显微镜显示，特定颗粒群体不受移植影响。起初，心肌细胞显示出肌丝、线粒体和肌浆网的严重异常。颗粒状肌浆网比对照心肌细胞丰富得多。这些变化大多随时间消退，因此，346天后移植的心肌细胞几乎正常。这些实验表明，心房心肌细胞的特定颗粒群体可能不含有任何可观量的儿茶酚胺，并且不依赖于神经系统或局部刺激。
