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曼氏血吸虫病期间荧光标记的异常分布(作者译)

[Unusual distribution of fluorescent marking during Schistosoma mansoni schistosomiasis (author's transl)].

作者信息

Niel G, Rosin G, Danis M, Gentilini M

出版信息

Pathol Biol (Paris). 1976 Apr;24(4):277-82.

PMID:778761
Abstract

The sera of some patients suffering from intestinal bilharziasis determine, on frozen sections of adult S. mansoni, a labelling of the digestive tract disclosed by the fluorescent sera anti-IgG and IgM. This labelling appears early after the primary infestation and may remain isolated. It is found again later, among West Indian patients of all ages infested by S. mansoni. Its development is followed in the hamster and the mouse, experimentally infested. This labelling is also present in the animal infested with S. haematobium, but it appears exceptional among adults urinary bilharzians. No cross reaction of non-specific origin has been observed. The interest, for the screening, of its research with the help of conjugates anti-IgM, has been proved. Its meaning is discussed.

摘要

一些患肠道血吸虫病患者的血清,在曼氏血吸虫成虫的冰冻切片上,可使经荧光抗IgG和IgM血清显示出消化道的标记。这种标记在初次感染后早期出现,且可能保持孤立状态。后来在所有年龄受曼氏血吸虫感染的西印度患者中再次发现。在实验感染的仓鼠和小鼠中追踪其发展情况。这种标记在感染埃及血吸虫的动物中也存在,但在成人泌尿生殖道血吸虫病患者中似乎很罕见。未观察到非特异性来源的交叉反应。已证明借助抗IgM缀合物进行该项研究用于筛查很有意义。对其意义进行了讨论。

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