Viglinskaia I V, Molodavkin G M, Seredenin S B, Voronina T A
Eksp Klin Farmakol. 1995 Jan-Feb;58(1):57-9.
A set of correlating indices has been developed to assess alcohol craving in rats who has a free access to it for 24 months. The set includes the estimation of voluntary daily alcohol intake before and after ethanol deprivation and the assessment of rats' behavior in a conflict situation and a plus-maze. The increased intake of alcohol after its deprivation has been established to correlate with a number of punished ethanol lickings in the conflict paradigm and functional locomotor asymmetry in the plus-maze.
已经开发出一套相关指标来评估那些可以自由获取酒精24个月的大鼠的酒精渴望程度。该指标集包括对乙醇剥夺前后每日自愿酒精摄入量的估计,以及对大鼠在冲突情境和十字迷宫中的行为评估。已经确定,剥夺酒精后酒精摄入量的增加与冲突范式中多次被惩罚的乙醇舔舐行为以及十字迷宫中的功能性运动不对称有关。