Goonetilleke A
Department of Neurology, North Manchester General Hospital.
Br J Hosp Med. 1995;53(7):314-7.
Motor neurone disease (MND) is a fatal neurological disorder, characterised by progressive weakness and wasting of muscles. The variety of hypotheses for its aetiopathogenesis are reflected in the large number of drugs tried in an attempt to modify disease progression. Although MND was first described by Charcot in the 1870s, there is as yet no known cure for the disease.
运动神经元病(MND)是一种致命的神经系统疾病,其特征是肌肉进行性无力和萎缩。针对其病因发病机制的多种假说反映在为试图改变疾病进展而尝试的大量药物中。尽管运动神经元病最早是在19世纪70年代由夏科描述的,但目前该病仍无已知的治愈方法。