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酵母组蛋白在细胞周期中的合成

Synthesis of yeast histones in the cell cycle.

作者信息

Moll R, Wintersberger E

出版信息

Proc Natl Acad Sci U S A. 1976 Jun;73(6):1863-7. doi: 10.1073/pnas.73.6.1863.

DOI:10.1073/pnas.73.6.1863
PMID:778847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC430407/
Abstract

The yeast, Saccharomyces cerevisiae, contains four types of histones resembling histones H3, H2b, H2a, and H4 of animal cells. These proteins are synthesized primarily, if not exclusively, in the S-phase of the cell cycle. This result is discussed with reference to the insensitivity of ongoing DNA replication in yeast to inhibitors of protein synthesis.

摘要

酵母，酿酒酵母，含有四种类似于动物细胞中组蛋白H3、H2b、H2a和H4的组蛋白。这些蛋白质主要（如果不是唯一的话）在细胞周期的S期合成。结合酵母中正在进行的DNA复制对蛋白质合成抑制剂不敏感这一现象对该结果进行了讨论。

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本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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The relationship between histone and DNA synthesis in HeLa cells.海拉细胞中组蛋白与DNA合成之间的关系。
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High resolution acrylamide gel electrophoresis of histones.组蛋白的高分辨率丙烯酰胺凝胶电泳
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Proc Natl Acad Sci U S A. 1967 Nov;58(5):1977-83. doi: 10.1073/pnas.58.5.1977.
7
Initiation and control of DNA synthesis.DNA合成的起始与调控
Annu Rev Biochem. 1969;38:569-604. doi: 10.1146/annurev.bi.38.070169.003033.
8
DNA synthesis and DNA-polymerase activity in synchronized yeast cells.同步化酵母细胞中的DNA合成与DNA聚合酶活性
Mol Gen Genet. 1974;132(2):137-45. doi: 10.1007/BF00272179.
9
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Glucose uptake in the cell cycle of Saccharomyces cerevisiae.
Exp Cell Res. 1974 May;86(1):199-202. doi: 10.1016/0014-4827(74)90673-9.