Vuilleumier P, Assal G
Service de Neurologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Clin Neurol Neurosurg. 1995 Feb;97(1):39-46. doi: 10.1016/0303-8467(94)00056-c.
We report a patient with complete callosal disconnection syndrome after severe closed head injury. MRI showed a complete destruction of the corpus callosum throughout its length. Although traumatic callosal lesions are a frequent finding in autopsy studies, as well as in some recent MRI studies, clinical signs of callosal disconnection are rarely observed after head injuries and a complete disconnection syndrome has not been reported yet. This case study and the review of other reported cases suggest that posttraumatic callosal disconnection is probably often overlooked. Our patient had also a severe memory disorder that might be partly related to the bilateral involvement of the fornix, as this structure is closely adjacent to the posterior corpus callosum, and was also shown by MRI to be very probably damaged.
我们报告一名严重闭合性颅脑损伤后出现完全胼胝体离断综合征的患者。MRI显示胼胝体全程完全破坏。尽管创伤性胼胝体病变在尸检研究以及一些近期的MRI研究中经常被发现,但颅脑损伤后胼胝体离断的临床体征很少被观察到,且尚未有完全离断综合征的报道。本病例研究及对其他报道病例的回顾表明,创伤后胼胝体离断可能常常被忽视。我们的患者还患有严重的记忆障碍,这可能部分与穹窿的双侧受累有关,因为该结构紧邻胼胝体后部,MRI也显示其很可能受损。