锝-99m半乳糖基新糖白蛋白肝脏闪烁扫描术在暴发性肝衰竭中的应用

Tc-99m galactosyl-neoglycoalbumin hepatic scintigraphy in fulminant hepatic failure.

作者信息

Moragas M, Pavía J, Ginés A, Ros D, Solá M, Huguet M, Pons F, Setoain J

机构信息

Nuclear Medicine Service, Hospital Clinic i Provincial, Barcelona, Spain.

出版信息

Clin Nucl Med. 1995 Apr;20(4):329-33. doi: 10.1097/00003072-199504000-00009.

DOI:10.1097/00003072-199504000-00009

PMID:7788990

Abstract

Tc-99m galactosyl-neoglycoalbumin (NGA) is a new liver imaging agent that specifically binds to a hepatocyte specific membrane receptor, the hepatic binding protein. Scintigraphy with Tc-99m NGA is a noninvasive method that provides functional images of the liver. This report deals with one case of fulminant hepatic failure in which hepatic scintigraphy with Tc-99m NGA predicted hepatic recovery before clinical and biochemical parameters, being a prognostic index in this patient.

摘要

锝-99m半乳糖基-新糖白蛋白（NGA）是一种新型肝脏显像剂，它能特异性地与肝细胞特异性膜受体——肝脏结合蛋白相结合。用锝-99m NGA进行闪烁扫描是一种可提供肝脏功能图像的非侵入性方法。本报告涉及一例暴发性肝衰竭病例，其中用锝-99m NGA进行肝脏闪烁扫描在临床和生化指标出现之前就预测了肝脏的恢复情况，是该患者的一个预后指标。