Maddaluno R, Nobili C, Cocucci P, Bianchi B
Department of Infectious Diseases, Hospital of Frosinone.
Clin Ter. 1995 Feb;146(2):153-6.
A case of Candida chorioretinitis in a patient suffering from meningococcal meningitis, admitted to the Infectious Disease Department of Frosinone Hospital, Italy, is reported. Five days after the onset of meningitis during antibiotic and cortisone treatment the patient experienced oropharyngeal candidiasis, ocular pain and blurring of vision; two days later positive scotoma appeared. Ophthalmoscopic examination revealed probable Candida chorioretinitis. Treatment with intravenous fluconazole at high doses was employed with complete recovery of the right eye, while visual acuity of the left eye was 2/10. The use of long-term fluconazole at the doses reported, commonly employed in the treatment of systemic mycoses, improves prognosis.
报告了一例念珠菌性脉络膜视网膜炎病例,患者患有脑膜炎球菌性脑膜炎,入住意大利弗罗西诺内医院传染病科。在脑膜炎发病五天后,患者在接受抗生素和可的松治疗期间出现口腔念珠菌病、眼痛和视力模糊;两天后出现阳性暗点。眼底镜检查显示可能为念珠菌性脉络膜视网膜炎。采用大剂量静脉注射氟康唑治疗,右眼完全恢复,而左眼视力为2/10。按报告剂量长期使用氟康唑,常用于治疗系统性真菌病,可改善预后。