序列同一性将CEBPD和FGFR1定位到8号染色体短臂近端的已定位人类基因座上。
Sequence identity locates CEBPD and FGFR1 to mapped human loci within proximal 8p.
作者信息
Wood S, Schertzer M, Yaremko M L
机构信息
Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
出版信息
Cytogenet Cell Genet. 1995;70(3-4):188-91. doi: 10.1159/000134030.
PMID:7789168
Abstract
The gene loci for human CEBPD (CCAAT enhancer binding protein, delta chain) and FGFR1 (fibroblast growth factor receptor) have been identified within two genetically mapped cosmids by sequence homology between rare cutter site regions and data base sequences for these loci. Cell hybrid and fluorescence in situ hybridization mapping places both of these loci within the chromosome region 8p11.2-->p11.1.
摘要
通过稀有切割位点区域与这些基因座的数据库序列之间的序列同源性，在两个基因定位的黏粒中确定了人类CEBPD（CCAAT增强子结合蛋白，δ链）和FGFR1（成纤维细胞生长因子受体）的基因座。细胞杂交和荧光原位杂交定位将这两个基因座都定位于染色体区域8p11.2→p11.1内。
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