Qu F, He X, Lü W, Wang Y
Department of Neurology, General Hospital of PLA, Shenyang.
Chin Med J (Engl). 1995 Apr;108(4):259-61.
Neurohypophysial arginine vasopressin (AVP) concentrations were determined by RIA in 9 patients with cerebral infarction, 11 patients with intracerebral hemorrhage, 5 patients with subarachnoid hemorrhage and 5 control subjects. The results showed that neurohypophysial AVP concentration in patients with cerebral infarction increased by 225.8% as compared with the control subjects (P < 0.05), and the AVP concentrations in patients with intracerebral and subarachnoid hemorrhage did not change significantly. Brain herniation as a result of intracranial hypertension, gastrointestinal bleeding and hyperglycemia (two clinical manifestations of stress) was seen more frequently in hemorrhagic stroke patients than in ischemic stroke patients. These findings suggest that the ischemic brain damage may contribute to the elevation of neurohypophysial AVP concentration in patients with cerebral infarction.
采用放射免疫分析法（RIA）测定了9例脑梗死患者、11例脑出血患者、5例蛛网膜下腔出血患者及5例对照者神经垂体精氨酸加压素（AVP）的浓度。结果显示，脑梗死患者神经垂体AVP浓度较对照者升高了225.8%（P<0.05），而脑出血和蛛网膜下腔出血患者的AVP浓度无明显变化。颅内高压导致的脑疝、胃肠道出血及高血糖（应激的两种临床表现）在出血性卒中患者中比缺血性卒中患者更常见。这些发现提示，缺血性脑损伤可能导致脑梗死患者神经垂体AVP浓度升高。
