Ma K, Qian G, He Z, Wang A
Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical College, Chongqing.
Chin Med J (Engl). 1995 Apr;108(4):282-5.
The authors studied the changes of gastric acid secretion and determined the levels of somatostatin (SS) and gastrin (Gn) in blood, gastric juice and pyloric antrum in 28 patients Roux-en-Y with cholangiojejunostomy (CJR-Y). Gastric acid hypersecretion was identified, and the level of SS was found dropped while the content of Gn increased in these specimens. It was considered that the reduction of SS synthesis and secretion might have a key effect on the mechanism of secondary gastric acid hypersecretion in patients after CJR-Y.
作者研究了28例接受胆管空肠吻合术（CJR-Y）的Roux-en-Y患者胃酸分泌的变化，并测定了血液、胃液和幽门窦中生长抑素（SS）和胃泌素（Gn）的水平。发现这些患者存在胃酸分泌过多的情况，且这些标本中SS水平下降而Gn含量增加。据认为，SS合成和分泌的减少可能对CJR-Y术后患者继发性胃酸分泌过多的机制起关键作用。
