Saunders K J, McCulloch D L, Kerr A M
Department of Vision Sciences, Glasgow Caledonian University, UK.
Dev Med Child Neurol. 1995 Jun;37(6):496-504. doi: 10.1111/j.1469-8749.1995.tb12037.x.
The authors examined refractive error, pattern onset visual evoked potentials, ocular posture and they performed internal and external eye examinations in 11 subjects with Rett syndrome (aged between four and 24 years) and 18 normal controls (aged between six and 20 years). Substantial refractive errors were common in the Rett syndrome group. Spectacle correction had never previously been worn and glasses were provided where appropriate. No subjects had nystagmus or optic nerve pallor and only one was strabismic. All subjects had recognisable and reproducible pattern-onset VEPs and latencies and amplitudes did not differ significantly from those of the controls. All demonstrated VEP thresholds of at least 24'. In contrast to other populations with profound disabilities, people with Rett syndrome have good function of the afferent visual pathways and, in view of their substantial refractive errors, are likely to benefit from spectacle correction.
作者对11名雷特综合征患者（年龄在4至24岁之间）和18名正常对照者（年龄在6至20岁之间）进行了屈光不正、图形起始视觉诱发电位、眼位检查，并进行了内外眼检查。严重屈光不正在雷特综合征组中很常见。此前从未佩戴过眼镜矫正，必要时为患者提供了眼镜。所有受试者均无眼球震颤或视神经苍白，只有1例患有斜视。所有受试者均有可识别且可重复的图形起始视觉诱发电位，其潜伏期和振幅与对照组相比无显著差异。所有受试者的视觉诱发电位阈值均至少为24'。与其他严重残疾人群不同，雷特综合征患者的传入视觉通路功能良好，鉴于他们存在严重屈光不正，很可能从眼镜矫正中获益。
