Leary W P, Asmal A C, Bees L
S Afr Med J. 1976 May 22;50(22):840-2.
Intramuscular injections of 10 mg morphine or 100 mg tilidine hydrochloride were administered in a double-blind fashion and in random order to 40 patients after minor surgical operations. The therapeutic effect of each analgesic was assessed by comparing the severity of pain immediately postoperatively with that 1, 2, 3 and 4 hours after injection of the relevant analgesic. Tilidine and morphine relieved pain to a similar degree. Within the limits of the protocol followed, morphine appeared superior to tilidine in some tests. No major side-effects occurred.
对40例接受小手术后的患者采用双盲法并按随机顺序进行了10毫克吗啡或100毫克盐酸替利定的肌肉注射。通过比较术后即刻与注射相关镇痛药后1、2、3和4小时的疼痛严重程度来评估每种镇痛药的治疗效果。替利定和吗啡缓解疼痛的程度相似。在所遵循的方案范围内，吗啡在某些测试中似乎优于替利定。未出现重大副作用。
