Martel J, Mierau D, Donat J
Canadian Memorial Chiropractic College, Toronto, Ontario.
J Manipulative Physiol Ther. 1995 Mar-Apr;18(3):168-71.
To discuss the similarities and differences in the clinical presentation of Charcot-Marie-Tooth Disease, an inherited peripheral neuropathy, and acquired lumbar spinal stenosis.
Patients with lumbar spinal stenosis causing nerve root entrapment often have leg pain and weakness during such activities as walking or standing. Additional symptoms of poor balance, foot deformity and signs of cerebellar and sensory ataxia suggest a diagnosis of peripheral neuropathy rather than nerve root entrapment.
Electrodiagnostic testing and nerve conduction studies reveal abnormal conduction velocities in cases of peripheral neuropathy such as Charcot-Marie-Tooth Disease.
Sciatica and leg weakness may be due to a variety of causes, including nerve root entrapment and peripheral neuropathy. A diagnosis of Charcot-Marie-Tooth Disease should be considered in a case of progressive lower limb weakness associated with loss of balance and sensory ataxia. This diagnosis can be confirmed using nerve conduction studies.
探讨遗传性周围神经病——夏科-马里-图斯病（Charcot-Marie-Tooth Disease）与后天性腰椎管狭窄症临床表现的异同。
因腰椎管狭窄导致神经根受压的患者在行走或站立等活动时常常会出现腿痛和腿部无力。平衡能力差、足部畸形以及小脑和感觉性共济失调的体征等其他症状提示为周围神经病而非神经根受压。
电诊断测试和神经传导研究显示，在诸如夏科-马里-图斯病等周围神经病病例中传导速度异常。
坐骨神经痛和腿部无力可能由多种原因引起，包括神经根受压和周围神经病。对于伴有平衡能力丧失和感觉性共济失调的进行性下肢无力病例，应考虑夏科-马里-图斯病的诊断。可通过神经传导研究来确诊该诊断。
