Watanabe H, Suga A, Tsuchihashi Y, Hori A, Kawakami K, Masaki H, Akiyama M, Ohishi K, Takahashi A, Nagatake T
Department of Internal Medicine, Nagasaki University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Apr;33(4):384-8.
We studied clinical aspects of radiation pneumonitis from 1983 to 1992. Fifty seven patients admitted to our hospital because of lung cancer were treated with radiotherapy, and radiation pneumonitis developed in 20 (35.1%). The incidence of radiation pneumonitis was closely related to male sex, chronic obstructive lung disease, and chemotherapy. Pneumonitis was not related to age, or to the area or amount of radiation. Eighteen cases (90%) of pneumonitis occurred during or within one month after radiotherapy. In all but five cases (25%), pneumonitis was limited to the area of radiation. Treatment was mainly with steroids. In 4 cases (20%), pneumonitis recurred when steroid therapy was reduced, and five patients (10%) died.
我们对1983年至1992年期间放射性肺炎的临床情况进行了研究。57例因肺癌入院的患者接受了放射治疗，其中20例（35.1%）发生了放射性肺炎。放射性肺炎的发病率与男性、慢性阻塞性肺疾病和化疗密切相关。肺炎与年龄、放疗面积或剂量无关。18例（90%）肺炎发生在放疗期间或放疗后1个月内。除5例（25%）外，所有病例的肺炎均局限于放疗区域。主要采用类固醇进行治疗。4例（20%）在类固醇治疗减量时肺炎复发，5例（10%）患者死亡。
