Heary R F, Maniker A H, Wolansky L J
Section of Neurological Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, USA.
Neurosurgery. 1995 May;36(5):1009-12; discussion 1012-3. doi: 10.1227/00006123-199505000-00018.
We report a case of a culture-proven intrasellar Candida albicans abscess. A 36-year-old woman presented with a history of headaches, menstrual irregularities, and mild symptoms of diabetes insipidus. She was neurologically intact at the time of a transsphenoidal surgery for a presumed pituitary adenoma. An extensive work-up revealed that although the patient was seronegative for human immunodeficiency virus, she was immunocompromised with a T-cell dysfunction. Fungal abscesses of the pituitary gland have rarely been reported. This is the first documented case of a patient who is seronegative for human immunodeficiency virus who becomes infected by an ordinarily innocuous fungus, Candida albicans.
我们报告一例经培养证实的鞍内白色念珠菌脓肿病例。一名36岁女性，有头痛、月经不规律及轻度尿崩症症状史。在因疑似垂体腺瘤接受经蝶窦手术时，她神经系统功能完好。全面检查发现，尽管该患者人类免疫缺陷病毒血清学检测为阴性，但她存在免疫功能低下及T细胞功能障碍。垂体真菌性脓肿鲜有报道。这是首例记录在案的人类免疫缺陷病毒血清学检测阴性的患者被通常无害的真菌白色念珠菌感染的病例。
