Martinez-Perez D, Fein N A, Boon L M, Mulliken J B
Division of Plastic Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02111, USA.
Pediatr Dermatol. 1995 Mar;12(1):1-6. doi: 10.1111/j.1525-1470.1995.tb00114.x.
The typical appearance of cutaneous hemangiomas of infancy is well known. We studied unusual manifestations of this common tumor. We reviewed over 500 hemangiomas in the registry of the Vascular Anomalies Program at Boston Children's Hospital. We found four uncommon morphologic variations: deep hemangiomas with normal overlying skin (n = 12); macular hemangiomas with a port-wine stainlike appearance (n = 6); bossed hemangiomas with telangiectasia and peripheral pallor (n = 5); and hemangiomas with persistent fast flow (n = 3). Deep and superficial (macular) varieties regressed at a normal rate. Telangiectatic (bossed) hemangiomas, however, involuted rapidly, usually before 1 year of age. Hemangiomas with persistent fast flow required either resection or sclerotherapy for complications in early childhood.
婴儿期皮肤血管瘤的典型表现众所周知。我们研究了这种常见肿瘤的不寻常表现。我们回顾了波士顿儿童医院血管异常项目登记处的500多个血管瘤。我们发现了四种不常见的形态学变异：皮肤正常的深部血管瘤（n = 12）；具有葡萄酒色斑样外观的斑状血管瘤（n = 6）；伴有毛细血管扩张和周边苍白的隆起性血管瘤（n = 5）；以及具有持续快速血流的血管瘤（n = 3）。深部和浅表（斑状）类型以正常速度消退。然而，毛细血管扩张性（隆起性）血管瘤通常在1岁前迅速消退。具有持续快速血流的血管瘤在儿童早期因并发症需要手术切除或硬化治疗。
