Titius B R, Göhring U J, Scharl A
Institut für Pathologie, Universität zu Köln.
Pathologe. 1995 May;16(3):230-4. doi: 10.1007/s002920050096.
The case is presented of a 26-year-old woman with myxoid liposarcoma of the right breast who developed a relapse with anaplastic spindle-cell mesenchymal tumor 7 months after primary therapy. Additionally, 13 months later a bilateral adeno-carcinoma of differing histological grade occurred in the breasts. To the best of our knowledge, no comparable sarcoma-carcinoma sequence in the mammary gland has been reported. For this reason this case is discussed, with special emphasis on possible causative factors and the relationship to the Li-Fraumeni syndrome.
本文报告了一例26岁患有右乳黏液样脂肪肉瘤的女性患者，其在初始治疗7个月后复发，出现间变性梭形细胞间质肿瘤。此外，13个月后双侧乳房发生了不同组织学分级的腺癌。据我们所知，尚未有乳腺中类似肉瘤-癌序列的报道。因此，本文对该病例进行了讨论，特别强调了可能的致病因素以及与李-弗劳梅尼综合征的关系。
