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[伴有髓周静脉引流的脊髓硬脊膜动静脉瘘]

[Spinal dural fistula with peri-medullar venous drainage].

作者信息

Arnaud O, Pelletier J, Dalecky A, Cherif A A, Azulay J P, Salamon G, Khalil R

机构信息

Service de Neuroradiologie et de Radiologie Vasculaire, CHU Timone, Marseille.

出版信息

Rev Neurol (Paris). 1994 Oct;150(10):713-20.

PMID:7792480
Abstract

Clinical and neuroradiological findings of 8 patients with a spinal dural arteriovenous fistula are reviewed. Disturbance of micturition or defecation and weakness of the legs were always present and the most frequent initial symptom was a progressive spastic paraparesis. Duration of symptoms before diagnosis was 2 years. Lumbar puncture showed elevation of proteins and myelography demonstrated dilated perimedullar posterior veins. In every case, magnetic resonance imaging of the spinal cord (T2- weighted images) revealed intramedullary high signal intensity of the conus medullaris and selective angiography confirmed the site of the dural fistula. Each patient was treated with endovascular method consisting in liquid adhesive embolization (0.2 cc of N-butyl cyanoacrylate) with hyperselective catheterism of the dorsospinal artery. Embolization procedure was successful in 6 cases with large improvement of leg weakness and partial regression of disturbed micturition and defecation. The pathophysiological mechanisms explaining the clinical signs are discussed.

摘要

回顾了8例脊髓硬脊膜动静脉瘘患者的临床和神经放射学表现。排尿或排便障碍以及腿部无力始终存在,最常见的初始症状是进行性痉挛性截瘫。诊断前症状持续时间为2年。腰椎穿刺显示蛋白升高,脊髓造影显示髓周后静脉扩张。在每例病例中,脊髓磁共振成像(T2加权图像)显示圆锥髓质内高信号强度,选择性血管造影证实了硬脊膜瘘的部位。每位患者均采用血管内治疗方法,即通过背脊髓动脉超选择性插管进行液体粘合剂栓塞(0.2 cc正丁基氰基丙烯酸酯)。6例栓塞手术成功,腿部无力有显著改善,排尿和排便障碍部分缓解。讨论了解释临床体征的病理生理机制。

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