胚胎发育不良性神经上皮肿瘤：三例报告

Dysembryoplastic neuroepithelial tumor: report of three cases.

作者信息

Abe M, Tabuchi K, Tsuji T, Shiraishi T, Koga H, Takagi M

机构信息

Department of Neurosurgery, Saga Medical School, Japan.

出版信息

Surg Neurol. 1995 Mar;43(3):240-5. doi: 10.1016/0090-3019(95)80005-2.

DOI:10.1016/0090-3019(95)80005-2

PMID:7792686

Abstract

BACKGROUND

Dysembryoplastic neuroepithelial tumor (DNT) is one of the mixed neuronal-glial tumors that should be differentiated from low-grade gliomas. The recognition and correct diagnosis of DNT is important because this tumor is curable by excision.

METHODS

We report three cases of histologically proven DNTs with various image studies performed preoperatively and describe characteristic findings of them, as well as those of previous reports.

RESULTS

In our three cases, computed tomography (CT) showed a well-defined, nonenhancing hypodense area. Magnetic resonance imaging (MRI) demonstrated a cortical mass of hypointensity on T1- and of marked hyperintensity on T2-weighted images. I-123-IMP or Tc-99m-HMPAO single-photon emission computed tomography (SPECT) images showed marked hypoperfusion of the lesion. Thallium-SPECT showed no uptake.

CONCLUSIONS

I-123-IMP, Tc-99m-HMPAO, and Thallium-SPECT images, as well as CT and MRI, may be helpful in distinguishing DNT from low-grade gliomas.

摘要

背景

胚胎发育不良性神经上皮肿瘤（DNT）是一种混合性神经元-胶质肿瘤，需与低级别胶质瘤相鉴别。认识并正确诊断DNT很重要，因为该肿瘤可通过手术切除治愈。

方法

我们报告3例经组织学证实的DNT病例，术前进行了多种影像学检查，并描述了这些病例以及既往报道病例的特征性表现。

结果

在我们的3例病例中，计算机断层扫描（CT）显示边界清晰、无强化的低密度区。磁共振成像（MRI）显示皮质肿物在T1加权像上呈低信号，在T2加权像上呈明显高信号。I-123-异碘安非他明（IMP）或锝-99m-六甲基丙烯胺肟（HMPAO）单光子发射计算机断层扫描（SPECT）图像显示病变部位灌注明显减低。铊-SPECT显示无摄取。