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Studies in experimental models of chronic rejection: use of rapamycin (sirolimus) and isoxazole derivatives (leflunomide and its analogue) for the suppression of graft vascular disease and obliterative bronchiolitis.

作者信息

Morris R E, Huang X, Gregory C R, Billingham M E, Rowan R, Shorthouse R, Berry G J

机构信息

Department of Cardiothoracic Surgery, Stanford University School of Medicine, California 94305-5247, USA.

出版信息

Transplant Proc. 1995 Jun;27(3):2068-9.

PMID:7792888
Abstract
摘要

相似文献

1
Studies in experimental models of chronic rejection: use of rapamycin (sirolimus) and isoxazole derivatives (leflunomide and its analogue) for the suppression of graft vascular disease and obliterative bronchiolitis.慢性排斥反应实验模型的研究:雷帕霉素(西罗莫司)和异恶唑衍生物(来氟米特及其类似物)用于抑制移植物血管病和闭塞性细支气管炎。
Transplant Proc. 1995 Jun;27(3):2068-9.
2
Comparison of rapamycin, RS 61443, cyclosporine, and low-dose heparin as treatment for transplant vasculopathy in a rat model of chronic allograft rejection.雷帕霉素、RS 61443、环孢素和低剂量肝素作为慢性同种异体移植排斥反应大鼠模型中移植血管病治疗方法的比较。
Transplant Proc. 1995 Feb;27(1):438-9.
3
Progressive change in tolerance mechanisms after withdrawing combination immunosuppression with cyclosporine and rapamycine or leflunomide.停用环孢素与雷帕霉素或来氟米特联合免疫抑制后耐受机制的渐进性变化。
Transplant Proc. 1996 Dec;28(6):3159.
4
Obliterative airway disease after heterotopic tracheal xenotransplantation in a concordant rodent model: pathogenesis and treatment.
Transplant Proc. 1996 Apr;28(2):729-30.
5
Effects of leflunomide and cyclosporine on aortic allograft chronic rejection in the rat.
Transplant Proc. 1994 Dec;26(6):3244-5.
6
Leflunomide in experimental transplantation. Control of rejection and alloantibody production, reversal of acute rejection, and interaction with cyclosporine.来氟米特在实验性移植中的应用。抑制排斥反应和同种抗体产生、逆转急性排斥反应以及与环孢素的相互作用。
Transplantation. 1994 Apr 27;57(8):1223-31.
7
Synergistic effect of 3M KCl-extracted donor antigens with cyclosporine or cyclosporine/rapamycin to prolong heart allograft survival in rats.
Transplant Proc. 1994 Oct;26(5):3053-5.
8
Rescue therapy with rapamycin blocks an ongoing process of heart allograft rejection.雷帕霉素挽救性治疗可阻断心脏同种异体移植排斥反应的持续进程。
Transplant Proc. 1993 Feb;25(1 Pt 1):729.
9
Rapamycin and cyclosporine synergistically prolong heart and kidney allograft survival.雷帕霉素和环孢素协同延长心脏和肾脏同种异体移植的存活时间。
Transplant Proc. 1991 Dec;23(6):3262-4.
10
Inhibition of graft coronary arteriosclerosis after heart transplantation.心脏移植后移植冠状动脉粥样硬化的抑制
Am Surg. 2004 Oct;70(10):833-40.

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Chronic Renal Transplant Rejection and Possible Anti-Proliferative Drug Targets.慢性肾移植排斥反应及可能的抗增殖药物靶点
Cureus. 2015 Nov 6;7(11):e376. doi: 10.7759/cureus.376.
2
[Immunosuppressives to prevent rejection reactions after allogeneic corneal transplantation].[用于预防同种异体角膜移植术后排斥反应的免疫抑制剂]
Ophthalmologe. 2014 Mar;111(3):270-82. doi: 10.1007/s00347-013-3016-6.
3
[Systemic immunosuppressives after penetrating keratoplasty].穿透性角膜移植术后的全身免疫抑制剂
Ophthalmologe. 2007 May;104(5):373-80. doi: 10.1007/s00347-007-1517-x.
4
The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis.异位气管同种异体移植作为闭塞性细支气管炎的动物模型。
Respir Res. 2001;2(3):169-83. doi: 10.1186/rr55. Epub 2001 Apr 5.
5
Role of nitric oxide in experimental obliterative bronchiolitis (chronic rejection) in the rat.一氧化氮在大鼠实验性闭塞性细支气管炎(慢性排斥反应)中的作用
J Clin Invest. 1997 Dec 15;100(12):2984-94. doi: 10.1172/JCI119852.
6
Prevention of transplant rejection: current treatment guidelines and future developments.移植排斥反应的预防:当前治疗指南与未来发展
Drugs. 1997 Oct;54(4):533-70. doi: 10.2165/00003495-199754040-00003.