[甲状腺和性腺激素对肝细胞染色体完整性的影响]
[The effect of thyroid and gonadal hormones on the chromosomal integrity of liver cells].
作者信息
Timchenko O I
出版信息
Tsitol Genet. 1995 Jan-Feb;29(1):41-5.
PMID:7792937
Abstract
The materials presented as well as the data of the author's previous investigations indicate different cytogenetic importance of the basic hormones of the thyroid and sexual glands (thyroxine, testosterone, and estradiol) when they are used in physiologic doses. Thyroxine possesses mutagenic and antimutagenic properties, testosterone possesses only mutagenic ones, while estradiol has no effect on chromosome integrity.
摘要
所呈现的材料以及作者先前研究的数据表明，甲状腺和性腺的基本激素（甲状腺素、睾酮和雌二醇）在生理剂量下使用时具有不同的细胞遗传学重要性。甲状腺素具有诱变和抗诱变特性，睾酮仅具有诱变特性，而雌二醇对染色体完整性没有影响。
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