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[放射学造影化疗栓塞对恶性肝脏肿瘤超微结构变化的影响]

[Effect of radiologic contrast chemoembolization on ultrastructural changes of malignant liver neoplasms].

作者信息

Stepanov R P, Granov D A

出版信息

Vestn Rentgenol Radiol. 1994 Nov-Dec(6):16-9.

PMID:7793049
Abstract

The authors confirm the efficacy of treating primary and metastatic cancer of the liver by selective blocking of vessels in the involved liver part with an oily x-ray contrast agent with a citostatic dioxadet. Profound irreversible injury to tumor tissue was observed. Only solitary tumor cells were left slightly injured. Excepting a narrow adjacent area, lesser amount of lipid tissue accumulated in the tumor; hepatocytes were sufficiently well preserved, showing signs of reparation and increased functional activity 1-2 weeks after chemoembolization.

摘要

作者证实,通过使用含细胞抑制剂二恶烷二乙胺的油性X射线造影剂选择性阻断受累肝脏部分的血管来治疗原发性和转移性肝癌是有效的。观察到肿瘤组织受到严重的不可逆损伤。仅留下少量轻微受损的孤立肿瘤细胞。除了狭窄的相邻区域外,肿瘤中积累的脂质组织较少;肝细胞保存得相当完好,在化疗栓塞后1至2周显示出修复迹象和功能活性增强。

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