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[铁蛋白免疫酶分析在脑肿瘤诊断中的应用]

[Immunoenzyme analysis of ferritin in diagnosing brain tumors].

作者信息

Morozov S G, Chekhonin V P, Belopasov V V, Panchenko L F, Kachkov I A, Biktimirov R G, Abramova O S

出版信息

Vopr Med Khim. 1995 Mar-Apr;41(2):43-5.

PMID:7793096
Abstract

A procedure was developed to purify ferritin from the human brain tissue. The preparation is a heavy chain of ferritin. The level of ferritin in biological fluids was evaluated using the sandwich solid-phase immunoassay. This fraction of ferritin was found in the cerebrospinal fluid of patients with brain tumors. Content of the ferritin heavy chain in cerebrospinal fluid correlated with the rate of brain tissue malignancy.

摘要

已开发出一种从人脑组织中纯化铁蛋白的方法。该制剂是铁蛋白的重链。使用夹心固相免疫测定法评估生物体液中铁蛋白的水平。在脑肿瘤患者的脑脊液中发现了这种铁蛋白组分。脑脊液中铁蛋白重链的含量与脑组织恶性程度相关。

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