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[锁骨下静脉血栓形成:PHLEKO(静脉血栓形成保守治疗)研究的流行病学数据]

[Subclavian vein thrombosis: epidemiologic data of the PHLEKO (phlebothrombosis conservative treatment) Study].

作者信息

Martin M, Brors G

机构信息

Geriatrische Klinik der Städtischen Kliniken Duisburg.

出版信息

Vasa. 1995;24(2):120-5.

PMID:7793142
Abstract

This is a report of 91 cases of subclavian vein thrombosis. The data are derived from the PHLECO-study (Phlebothrombosis-Conservative treatment) which is a multicenter investigation on the fate of 2088 deep vein thromboses as diagnosed by phlebography. In this cohort the subclavian vein thrombosis incidence was recorded at 4.36%. The interval between first symptoms and hospital admission lasted 3.90 days. The average patient's age was 46.3 years. The genders were evenly distributed. The causes of subclavian vein thromboses were in 29.7% traumatic (effort thrombosis, catheter manipulation), in 31.9% symptomatic (accompanying other diseases), and in 38.4% idiopathic (cause unknown). Fibrinolytic therapy was carried out in 49.4% of the cases, the remainder received anticoagulants. Patients with acute subclavian vein thrombosis and conservative treatment (no fibrinolytic therapy) stayed for 18.8 days in the hospital. No instances of pulmonary embolism, either fatal or non-fatal, were recorded.

摘要

本文报告了91例锁骨下静脉血栓形成病例。数据来源于PHLECO研究(静脉血栓形成-保守治疗),这是一项关于2088例经静脉造影诊断的深静脉血栓形成转归的多中心调查。在该队列中,锁骨下静脉血栓形成的发生率记录为4.36%。首发症状与入院之间的间隔持续3.90天。患者的平均年龄为46.3岁。性别分布均匀。锁骨下静脉血栓形成的原因中,29.7%为创伤性(用力性血栓形成、导管操作),31.9%为症状性(伴有其他疾病),38.4%为特发性(原因不明)。49.4%的病例进行了纤溶治疗,其余患者接受了抗凝治疗。急性锁骨下静脉血栓形成且接受保守治疗(未进行纤溶治疗)的患者住院18.8天。未记录到致命或非致命肺栓塞病例。

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