Vuong P N, Janzen J, Bical O, Susa-Uva M
Unité d'Anatomie et de Cytologie Pathologiques, Hôpital Saint-Michel, Paris.
Vasa. 1995;24(2):194-8.
The authors report a case of atypical coarctation of the thoracic aorta discovered by chance in a 37-year-old man, victim of a car accident. The angiogram revealed a "string-of-beads" contour in the coarctate area while the left subclavian artery presented a severe stenosis at its origin. Vascular checkup examination failed to identify any additional vascular anomaly. The patient underwent surgical resection, with a Dacron prosthetic bypass. Histological study of the specimen removed, showed a typical perimedial and extensive medial types of fibromuscular dysplasia (FMD) of the aorta. Pathogenesis of this disease is discussed.
作者报告了一例在一名37岁男性车祸受害者中偶然发现的非典型胸主动脉缩窄病例。血管造影显示缩窄区域呈“串珠样”轮廓，而左锁骨下动脉在其起始处有严重狭窄。血管检查未发现任何其他血管异常。患者接受了手术切除，并进行了涤纶人工血管旁路移植术。对切除标本的组织学研究显示，主动脉存在典型的中膜周围型和广泛的中膜型纤维肌发育不良（FMD）。本文讨论了该疾病的发病机制。
