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[子宫内膜腺癌的淋巴细胞组织细胞浸润]

[Lymphohistiocytic infiltration of endometrial adenocarcinoma].

作者信息

Böhme M, Löttge M, Schmidt D, Röse I, Weise W, Morenz J

机构信息

Hauptabteilung für Gynäkologie der Klinik St. Marienstift.

出版信息

Zentralbl Gynakol. 1995;117(5):247-52.

PMID:7793166
Abstract

Mononuclear cells adjacent to endometrial adenocarcinoma were evaluated in 8 biopsies by the immunoperoxidase technique. Between benign and malignant tissue a remarkable infiltration of CD45+, CD3+, CD4+, CD8+, and CD14+ cells could be observed. B cells (CD19) and NK cells (CD57) were rare. Tumor-infiltrating lymphocytes were only sparsely distributed. The findings suggest a cellular, yet ineffective, immune reaction of the host against the tumor at the borderline between benign and malignant tissue.

摘要

采用免疫过氧化物酶技术对8份活检标本中子宫内膜腺癌旁的单核细胞进行了评估。在良性和恶性组织之间,可以观察到CD45 +、CD3 +、CD4 +、CD8 +和CD14 +细胞的显著浸润。B细胞(CD19)和NK细胞(CD57)很少见。肿瘤浸润淋巴细胞分布稀疏。这些发现提示宿主在良性和恶性组织交界处对肿瘤产生了细胞免疫反应,但这种反应是无效的。

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