Takata M, Miyasaka K, Sakai H, Fujiwara H, Ito Y, Kawano T
Department of Anesthesia/Intensive Care, National Children's Hospital, Tokyo, Japan.
Acta Paediatr Jpn. 1995 Apr;37(2):171-3. doi: 10.1111/j.1442-200x.1995.tb03291.x.
Persistent pulmonary hypertension of the newborn (PPHN) may occasionally require an invasive treatment with extracorporeal membrane oxygenation (ECMO). Inhaled nitric oxide (NO) has recently been introduced as a selective pulmonary vasodilator for treatment of PPHN. We describe a case of PPHN in which neither inhaled NO nor ECMO was effective in reversing pulmonary hypertension. The clinical course of the patient suggested a potential role of NO inhalation in predicting the outcome of ECMO treatment for PPHN.
新生儿持续性肺动脉高压（PPHN）偶尔可能需要采用体外膜肺氧合（ECMO）进行侵入性治疗。吸入一氧化氮（NO）最近已被用作治疗PPHN的选择性肺血管扩张剂。我们描述了一例PPHN病例，其中吸入NO和ECMO均未能有效逆转肺动脉高压。该患者的临床病程提示吸入NO在预测PPHN的ECMO治疗结果方面可能具有潜在作用。
