Haramis H T, Apesos J
Department of Plastic and Reconstructive Surgery, Wright State University/Kettering Medical Center, Dayton, OH, USA.
Ann Plast Surg. 1995 Apr;34(4):424-30. doi: 10.1097/00000637-199504000-00016.
Cleft palate and congenital lateral alveolar synechia syndrome remains a rare occurrence. Our patient represents only the fourth case of bilateral alveolar synechia with isolated cleft palate in the world literature and, as such, is only the second patient from the United States. More commonly, additional anomalies are associated. Just more than 50 cases involving intraoral synechiae have been reported. This group of cases has implications on fetal facial growth and cleft palate development because there are no documented cases of lateral interalveolar synechiae without cleft palate. Earlier reports can be grouped as variants along the spectrum. Theories of etiology are discussed.
腭裂和先天性外侧牙槽粘连综合征仍然较为罕见。我们的患者是世界文献中仅有的第四例双侧牙槽粘连合并孤立性腭裂的病例,因此,也是来自美国的第二例患者。更常见的情况是伴有其他异常。据报道,涉及口腔内粘连的病例仅有50多例。这组病例对胎儿面部生长和腭裂发育有影响,因为尚无无腭裂的外侧牙槽间粘连的记录病例。早期报告可归为该谱系中的不同变体。本文还讨论了病因学理论。