Little J T, Satlin A, Sunderland T, Volicer L
Biological Psychiatry Branch, NIMH, Bethesda, Maryland 20892, USA.
J Geriatr Psychiatry Neurol. 1995 Apr;8(2):103-6. doi: 10.1177/089198879500800205.
A retrospective review of 71 patients with probable Alzheimer's disease was analyzed with respect to nursing evaluations of sundowning status (recurring confusion or agitation in the late afternoon or early evening). The prevalence of sundowning (including probable sundowners) was 24%. Sundowners and non-sundowners differed with regard to number of sedatives received daily, particularly chloral hydrate, and the number of days on the inpatient unit. There were no differences between sundowners and non-sundowners with respect to other types of medications, medical diagnoses, current age, age of onset of Alzheimer's disease, or Mini-Mental State Exam. Restlessness was the most common sundowning behavior, although multiple behavioral disturbances were seen. This survey suggests that the sundown syndrome is a common problem in severely demented Alzheimer's patients and requires further study.
对71例可能患有阿尔茨海默病的患者进行了回顾性研究，分析了日落综合征状态（下午晚些时候或傍晚反复出现的混乱或躁动）的护理评估情况。日落综合征（包括可能的日落综合征患者）的患病率为24%。日落综合征患者和非日落综合征患者在每日接受镇静剂的数量上存在差异，尤其是水合氯醛，以及在住院部的住院天数。在其他类型的药物、医学诊断、当前年龄、阿尔茨海默病发病年龄或简易精神状态检查方面，日落综合征患者和非日落综合征患者之间没有差异。躁动是最常见的日落综合征行为，不过也观察到了多种行为障碍。这项调查表明，日落综合征在重度痴呆的阿尔茨海默病患者中是一个常见问题，需要进一步研究。
