Chutivongse S, Wilde H, Benjavongkulchai M, Chomchey P, Punthawong S
Queen Saovabha Memorial Institute, WHO Collaborating Center for Research in Rabies, Bangkok, Thailand.
Clin Infect Dis. 1995 Apr;20(4):818-20. doi: 10.1093/clinids/20.4.818.
This prospective study of 202 pregnant Thai women who received postexposure treatment for rabies with a tissue culture-derived rabies vaccine and human or equine rabies immune globulin revealed an adverse reaction rate similar to that seen among nonpregnant Thai patients who received the same treatment. Tissue culture-derived rabies vaccines as well as immune globulins are safe to use for postexposure prophylaxis during pregnancy. Such treatment should never be withheld or delayed if the patient possibly was exposed to rabies.
这项针对202名泰国孕妇的前瞻性研究显示，她们接受了组织培养狂犬病疫苗以及人用或马用狂犬病免疫球蛋白进行狂犬病暴露后治疗，其不良反应发生率与接受相同治疗的非孕泰国患者相似。组织培养狂犬病疫苗和免疫球蛋白在孕期用于暴露后预防是安全的。如果患者可能暴露于狂犬病，绝不应扣留或延迟此类治疗。
