Szucs T D
Ludwig-Maximilians-Universität, Munich, Germany.
Blood Coagul Fibrinolysis. 1994 Dec;5 Suppl 4:S51-5. doi: 10.1097/00001721-199412004-00015.
Future clinical practice in haemophilia care must make optimum use of resources and provide the highest quality products and services in an efficient and effective manner. Studies show that prophylactic therapy, compared with on-demand therapy, results in less time off work--that is, a smaller loss in productivity. However, prophylactic therapy requires a three- to five-fold greater annual amount of factor VIII than does on-demand therapy. Further study is needed to determine the optimum therapeutic strategy that gives the best cost v. benefit situation.
未来血友病护理的临床实践必须优化资源利用，以高效且有效的方式提供最高质量的产品和服务。研究表明，与按需治疗相比，预防性治疗导致的误工时间更少，即生产力损失更小。然而，预防性治疗所需的每年凝血因子 VIII 用量比按需治疗多三到五倍。需要进一步研究以确定能带来最佳成本效益情况的最佳治疗策略。
