Sutanto W, de Kloet E R
Division of Pharmacology, Sylvius Laboratories, Leiden, The Netherlands.
Pharm World Sci. 1995 Mar 24;17(2):31-41. doi: 10.1007/BF01875052.
This review aims to highlight a selection of antagonists for the mineralocorticoid and glucocorticoid receptors. Concepts of these receptor systems are described, as is the mechanism of action of these steroids in the brain and periphery. Examples of commonly available and newly synthesized antimineralocorticoids and antiglucocorticoids are given, together with their pharmacological profiles and, when appropriate, clinical and therapeutic applications.
本综述旨在重点介绍一系列盐皮质激素和糖皮质激素受体拮抗剂。文中描述了这些受体系统的概念，以及这些类固醇在大脑和外周的作用机制。给出了常用的和新合成的抗盐皮质激素及抗糖皮质激素的例子，以及它们的药理学特性，并在适当的时候介绍了其临床和治疗应用。
