幽门窦去神经支配对胃对食物分泌反应的影响。

Effect of denervation of pyloric antrum on the gastric secretory response to food.

作者信息

Hunt D R, Forrest A P

出版信息

Aust J Exp Biol Med Sci. 1975 Dec;53(6):499-514. doi: 10.1038/icb.1975.55.

DOI:10.1038/icb.1975.55

Abstract

The effect of selective denervation of the pyloric antrum on secretory response to three types of food was determined in 3 dogs with innervated and 4 with denervated stomach pouches. With the antrum in situ this procedure has surprisingly little effect on the total meal responses in innervated pouches, on the variation in response induced by altered buffering capacity of the meals, or on the effect of subsequent vagotomy. However, the antrum appears less sensitive to local stimuli after denervation, as evidenced by the reduced meal response from the denervated indicator pouch after denervation of the antrum.

摘要

在3只具有完整神经支配的犬和4只幽门窦去神经支配的胃小囊中，测定了幽门窦选择性去神经支配对三种食物分泌反应的影响。当幽门窦保持原位时，该操作对具有完整神经支配的胃小囊的总体进食反应、由食物缓冲能力改变引起的反应变化或随后迷走神经切断术的效果，出人意料地几乎没有影响。然而，去神经支配后，幽门窦对局部刺激的敏感性似乎降低，这表现为幽门窦去神经支配后去神经支配的指示性胃小囊的进食反应减弱。