[塑料薄膜诱导的小鼠辐射嵌合体肉瘤的组织发生]
[Histogenesis of sarcomas, induced by plastic films, in murine radiation chimeras].
作者信息
Moĭzhess T G, Prigozhina E L
出版信息
Biull Eksp Biol Med. 1976 May;81(5):587-9.
PMID:779870
Abstract
Sarcomas were induced in radiation chimeras CBA/CBAT6T6 by subcutaneous implantation of plastic films 13 months after the irradiation and donor bone marrow transplantation. Of the 12 tumours examined, 11 possessed host kariotype and one--donor karyotype. Development of connective tissue cells from the bone marrow precursors presumably played no significant role in the histogenesis of plastic sarcomas.
摘要
在照射及供体骨髓移植13个月后，通过皮下植入塑料薄膜，在辐射嵌合体CBA/CBAT6T6中诱发肉瘤。在所检查的12个肿瘤中，11个具有宿主核型，1个具有供体核型。骨髓前体细胞发育为结缔组织细胞大概在塑料肉瘤的组织发生中不起重要作用。
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