Sato M, Konno S, Maemura T, Goto K, Hayashibe Y, Ito J
Department of Cardiovascular Surgery, Hiroo Cosmopolitan Hospital, Tokyo, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1994 Oct;42(10):2000-2.
A 60-year-old female patient diagnosed as having mitral stenosis with chronic idiopathic thrombocytopenic purpura (ITP), with a platelet count of 6.8 x 10(4)/mm3, was scheduled to undergo mitral valve replacement. High-dose immunoglobulin infusion (400 mg/kg/day for five days) was begun four days before the operation and increased the platelet count to 9.1 x 10(4)/mm3 just before the operation. Intraoperative hemostasis was excellent, and the postoperative course was uneventful. High-dose immunoglobulin therapy appears to be a first choice for controlling hemorrhagic tendency in ITP patients undergoing heart surgery.
一名60岁女性患者被诊断为二尖瓣狭窄合并慢性特发性血小板减少性紫癜（ITP），血小板计数为6.8×10⁴/mm³，计划接受二尖瓣置换术。在手术前四天开始大剂量输注免疫球蛋白（400mg/kg/天，共五天），术前血小板计数升至9.1×10⁴/mm³。术中止血良好，术后过程顺利。大剂量免疫球蛋白治疗似乎是控制接受心脏手术的ITP患者出血倾向的首选方法。
