Abernathy-Carver K J, Fan L L, Boguniewicz M, Larsen G L, Leung D Y
Department of Pediatrics, National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80206.
Pediatr Pulmonol. 1994 Sep;18(3):135-8. doi: 10.1002/ppul.1950180303.
Asthma is increasingly treated as an inflammatory disease with inhaled and/or systemic corticosteroids. We report 3 cases of unusual pneumonias associated with high doses of oral steroids. Two patients contracted Legionella pneumonia and one patient contracted Pneumocystis carinii pneumonia. With increasing usage, it is important for physicians to be aware of the possible infectious complications of high dose steroids. This report highlights the risk of corticosteroid treatment in asthma in predisposing to opportunistic infections that have not heretofore been readily associated with asthma.
哮喘越来越多地被当作一种炎症性疾病，使用吸入性和/或全身性皮质类固醇进行治疗。我们报告3例与高剂量口服类固醇相关的不寻常肺炎病例。两名患者感染了军团菌肺炎，一名患者感染了卡氏肺孢子虫肺炎。随着皮质类固醇使用的增加，医生了解高剂量类固醇可能导致的感染并发症很重要。本报告强调了哮喘患者使用皮质类固醇治疗易引发机会性感染的风险，而此前这些感染与哮喘并无明显关联。
