Chapman H D, Hacker A B
Department of Poultry Science, University of Arkansas, Fayetteville 72701.
Poult Sci. 1994 Sep;73(9):1404-8. doi: 10.3382/ps.0731404.
The spectrum of resistance to seven currently used anticoccidial drugs in isolates of Eimeria obtained from farms two broiler complexes was examined. All isolates were resistant to monensin, salinomycin, and narasin. Lasalocid was more effective in controlling coccidiosis than the other ionophores, although most isolates were classified as resistant to the drug. The majority of isolates were sensitive or showed reduced sensitivity to robenidine, clopidol, and decoquinate. It was concluded that for drugs that have been used extensively (e.g., monensin and salinomycin), examination of isolates from one or two farms may give results applicable to the entire complex. For drugs that have been used infrequently, however (such as robenidine, clopidol, and decoquinate), examination of isolates from at least five farms would be desirable to establish the spectrum of drug sensitivity.
对从两个肉鸡养殖区的农场分离出的艾美耳球虫菌株，检测了其对七种目前使用的抗球虫药的耐药谱。所有分离株对莫能菌素、盐霉素和那拉菌素均有耐药性。拉沙里菌素在控制球虫病方面比其他离子载体更有效，尽管大多数分离株被归类为对该药耐药。大多数分离株对罗苯尼丁、氯羟吡啶和地克珠利敏感或显示敏感性降低。得出的结论是，对于已广泛使用的药物（如莫能菌素和盐霉素），检测一两个农场的分离株可能得出适用于整个养殖区的结果。然而，对于使用频率较低的药物（如罗苯尼丁、氯羟吡啶和地克珠利），检测至少五个农场的分离株以确定药物敏感性谱是可取的。
