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低功率镓铝砷激光治疗膝关节疼痛性骨关节炎。一项双盲安慰剂对照研究。

Low power Ga-Al-As laser treatment of painful osteoarthritis of the knee. A double-blind placebo-controlled study.

作者信息

Bülow P M, Jensen H, Danneskiold-Samsøe B

机构信息

Muscle Research Laboratory, Frederiksberg Hospital, Copenhagen, Denmark.

出版信息

Scand J Rehabil Med. 1994 Sep;26(3):155-9.

PMID:7801065
Abstract

The aim of this double-blind study was to evaluate the effect of low power Ga-Al-As laser treatment on chronic pain related to osteoarthritis of the knee with periarticular tender points. Twenty-nine out-patients with uni- or bilateral osteoarthritis of the knee were included and randomly assigned to treatment with either laser or placebo laser. Fourteen patients received active laser treatment and all patients included completed the study. The effect variables were daily levels of pain, analgesic requirements, palpation tenderness and isokinetic quadriceps strength. Each patient participated in the study for 9 weeks and registered daily level of pain and consumption of analgesics. In weeks 4, 5 and 6 the patients received a total of nine treatments, each of 15 min and administered to periarticular tender points. The dose per treatment was 22.5 joule. No significant differences in any of the effect variables were found between the two groups before, during or after treatment. With regard to the patients' overall assessment there was a clearly demonstrable positive effect of treatment in both groups. This is likely to be due to a placebo effect.

摘要

这项双盲研究的目的是评估低功率镓铝砷激光治疗对伴有关节周围压痛点的膝关节骨关节炎相关慢性疼痛的影响。纳入了29名单侧或双侧膝关节骨关节炎门诊患者,并将他们随机分配接受激光治疗或安慰剂激光治疗。14名患者接受了主动激光治疗,所有纳入研究的患者均完成了研究。效应变量包括每日疼痛程度、镇痛药物需求、触诊压痛和等速股四头肌力量。每位患者参与研究9周,记录每日疼痛程度和镇痛药物消耗量。在第4、5和6周,患者共接受9次治疗,每次15分钟,治疗关节周围压痛点。每次治疗剂量为22.5焦耳。两组在治疗前、治疗期间或治疗后,任何效应变量均未发现显著差异。关于患者的总体评估,两组治疗均有明显的积极效果。这可能是由于安慰剂效应。

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