Schultz J H, Schmidt H G, Jürgens C, Kortmann H R
Abteilung für Unfall- und Wiederherstellungschirurgie, Berufsgenossenschaftliches Unfallkrankenhaus Hamburg.
Zentralbl Chir. 1994;119(10):714-21.
The treatment of nonunions complicated by infection and bone loss is divided into two stages. Having calmed down the infection by stabilizing, removal of infected and necrotic tissue and local antibacterial measures, the bone loss has to be filled up. Bridging the gap by means of autogenous cancellous bone grafting is complicated by a high rate of refractures depending on the length of bone loss. Therefore after changing the method and using the Ilizarov procedure it is of interest, whether this method offers advantages. Our experience is to be reported and discussed.
According to the clinical course two groups of patients with nonunions of the tibia complicated by infection and bone loss were compared. 25 previously evaluated patients of the years 1980/81 whose tibial bone loss was bridged by cancellous bone grafting (1st group) were compared with 16 patients who were treated by the Ilizarov method from May 1990 to October 1993 (2nd group). The average age was nearly the same (32.6/32.9 years). In the first group the average of bone loss measured 4 cm, in the second 7.8 cm. The number of initial operations to eliminate infection and the duration of fixator application from the beginning of bridging bone loss were compared as well as early and late complications, especially the rate of refracture and reinfection.
1.2 operations were needed to eliminate infection in the first group, in the second only one was necessary. The handling of the Ilizarov device is more difficult and needs training. The higher rate of early complications at the beginning decreased with increasing experience. The average of fixation time could be reduced by about ten days per cm of bone loss using the Ilizarov technique. By segmental transport new cortical bone is generated which surpasses cancellous bone grafting in regard to stability. This seems to be an important reason that refracture did not occur in the second group. Furthermore, reinfection could be avoided up to now obviously due to sufficient segmental resection of infected and necrotic tissue. Limited stores of autogenous cancellous bone are not to be feared. The total number of operations can be reduced. At the docking side early single cancellous bone grafting is recommended.
感染合并骨缺损的骨不连治疗分为两个阶段。通过稳定病情、清除感染及坏死组织和局部抗菌措施控制感染后,必须填充骨缺损。采用自体松质骨移植来桥接骨缺损间隙,会因骨缺损长度不同而导致较高的再骨折发生率。因此,在改变治疗方法并采用伊里扎洛夫技术后,探讨该方法是否具有优势很有意义。现将我们的经验进行报告和讨论。
根据临床病程,对两组合并感染和骨缺损的胫骨骨不连患者进行比较。将1980/1981年之前评估的25例采用松质骨移植桥接胫骨骨缺损的患者(第一组)与于1990年5月至1993年10月采用伊里扎洛夫技术治疗的16例患者(第二组)进行比较。两组平均年龄相近(32.6/32.9岁)。第一组平均骨缺损为4厘米,第二组为7.8厘米。比较了消除感染的初次手术次数、从开始桥接骨缺损起固定器的应用时长,以及早期和晚期并发症,尤其是再骨折和再感染率。
第一组消除感染平均需要1.2次手术,第二组仅需1次。伊里扎洛夫器械操作更困难,需要培训。随着经验增加,开始时较高的早期并发症发生率有所降低。使用伊里扎洛夫技术,每厘米骨缺损的固定时间平均可减少约10天。通过节段性骨搬运可生成新的皮质骨,其稳定性超过松质骨移植。这似乎是第二组未发生再骨折的重要原因。此外,由于对感染及坏死组织进行了充分的节段性切除,目前明显可避免再感染。无需担心自体松质骨储备有限问题。可减少手术总次数,并建议在对接端早期进行单次松质骨移植。