Hellström B, Jordahl-Carlsson M, Nergårdh A
Dev Med Child Neurol. 1976 Jun;18(3):302-4. doi: 10.1111/j.1469-8749.1976.tb03651.x.
In 39 infants and children with myelomeningocele, no lower incidence of urinary tract infection was obtained by a trial of prophylaxis treatment with nitrofurantoin. Instead, nitrofurantoin-resistant strains appeared in some children, with the accompanying higher risk of re-infection.
在39名患有脊髓脊膜膨出的婴幼儿中,使用呋喃妥因进行预防性治疗并未降低尿路感染的发生率。相反,一些儿童出现了对呋喃妥因耐药的菌株,随之而来的是再次感染的风险更高。