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热探头热凝治疗巨大消化性溃疡出血患者的长期结果:一项前瞻性观察

Long-term results of heater probe thermocoagulation for patients with massive peptic ulcer bleeding: a prospective observation.

作者信息

Lin H J, Perng C L, Wang K, Lee S D, Lee C H

机构信息

Department of Medicine, Veterans General Hospital-Taipei, Taiwan, Republic of China.

出版信息

Am J Gastroenterol. 1995 Jan;90(1):44-7.

PMID:7801948
Abstract

OBJECTIVE

The long-term rebleeding rate of a bleeding ulcer after endoscopic hemostasis is, so far, not clear. The goal of this study is to present the natural history of bleeding ulcers after heater probe thermocoagulation.

METHODS

Between September 1986 and June 1991, we used heater probe to treat 202 patients with active bleeding or nonbleeding visible vessels at the ulcer craters. We were able to follow 159 patients for 2-7 yr (mean +/- SD: 54.5 +/- 19.9 months). Patients with active bleeding or nonbleeding visible vessels who did not receive endoscopic hemostasis or surgery in our previous studies served as controls.

RESULTS

The energy applied to each patient in the heater probe group was 886 +/- 844 J (mean +/- SD). The ultimate hemostatic rate in the heater probe group was 91.2% (145/159). In the period of long-term follow-up, there were 32 episodes of rebleeding in 24 patients (16.6%). Most rebleeding episodes (22/32) subsided spontaneously. Only one rebleeding patient died before a surgical attempt. The rebleeding rate was less than that of the controls (43/87, p < 0.0001).

CONCLUSION

Heater probe thermocoagulation is very effective in arrest of peptic ulcer bleeding. In the long-term follow-up, heater probe thermocoagulation can decrease rebleeding rate in most patients with peptic ulcer hemorrhage.

摘要

目的

迄今为止,内镜止血后出血性溃疡的长期再出血率尚不清楚。本研究的目的是呈现热探头热凝术后出血性溃疡的自然病程。

方法

1986年9月至1991年6月期间,我们使用热探头治疗了202例溃疡灶有活动性出血或可见非出血血管的患者。我们对159例患者进行了2至7年的随访(平均±标准差:54.5±19.9个月)。在我们之前的研究中,有活动性出血或可见非出血血管但未接受内镜止血或手术的患者作为对照。

结果

热探头组中每位患者施加的能量为886±844焦耳(平均±标准差)。热探头组的最终止血率为91.2%(145/159)。在长期随访期间,24例患者出现32次再出血事件(16.6%)。大多数再出血事件(22/32)自行缓解。只有1例再出血患者在尝试手术前死亡。再出血率低于对照组(43/87,p<0.0001)。

结论

热探头热凝术在消化性溃疡出血的止血方面非常有效。在长期随访中,热探头热凝术可降低大多数消化性溃疡出血患者的再出血率。

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