Svetlov V A, Alisov A P, Kozlov S P, Tsibuliak V N
Anesteziol Reanimatol. 1994 Jul-Aug(4):46-50.
Efficacy of central analgesia and adequacy of anesthesiologic protection in operations making use of microsurgical techniques were analyzed by double blind method using the criterion 'requirement in narcotics' in 88 specially selected patients divided into 4 groups. Group 1 (n = 24) were patients operated on under electro-medicamentous anesthesia after Kastrubin-Kordyukov; group 2 (n = 21) were operated on under electro-medicamentous anesthesia after Limoges' technique modified by M.I. Kuzin et al.; group 3 consisted of 14 patients operated on under combined anesthesia based on NLA agents and simultaneous simulation of transcerebral electropulse exposure (placebo group); and group 4 (n = 29) were patients operated on under combined NLA anesthesia (controls). To assess the function of systems of adaptation to surgical trauma blood plasma levels of ACTH and cyclic nucleotides were measured at 7 stages of anesthesia.
采用双盲法，以“麻醉药品需求量”为标准，对88例经特殊挑选并分为4组的患者进行分析，以研究在运用显微外科技术的手术中，中枢镇痛的效果及麻醉保护的充分性。第1组（n = 24）为在Kastrubin-Kordyukov法后的电药物麻醉下接受手术的患者；第2组（n = 21）为在M.I. Kuzin等人改良的Limoges技术后的电药物麻醉下接受手术的患者；第3组由14例在基于NLA制剂的复合麻醉及同时模拟经脑电脉冲照射下接受手术的患者组成（安慰剂组）；第4组（n = 29）为在NLA复合麻醉下接受手术的患者（对照组）。为评估对手术创伤的适应系统功能，在麻醉的7个阶段测量了促肾上腺皮质激素和环核苷酸的血浆水平。
