酿酒酵母孢子形成对谷胱甘肽的绝对需求
Absolute glutathione requirement for sporulation of a yeast Saccharomyces cerevisiae.
作者信息
Suizu T, Tsutsumi H, Ohtake Y, Kawado A, Imayasu S, Kimura A, Murata K
机构信息
Gekkeikan Institute, Gekkeikan Co., Ltd., Kyoto, Japan.
出版信息
Biochem Biophys Res Commun. 1994 Dec 15;205(2):1151-4. doi: 10.1006/bbrc.1994.2786.
The glutathione (GSH)-deficient yeast cells of Saccharomyces cerevisiae completely failed to sporulate in nutrition-deprived medium containing potassium acetate (SPO medium). The sporulation defect of the yeast was restored only when the yeast cells were incubated in SPO medium in the presence of GSH or its derivative such as oxidized GSH and gamma-L-glutamyl-L-cysteine. It was concluded that GSH was indispensably required to enter into meiosis and/or sporulation processes of the yeast Saccharomyces cerevisiae.
酿酒酵母中缺乏谷胱甘肽（GSH）的酵母细胞在含有醋酸钾的营养缺乏培养基（SPO培养基）中完全无法形成孢子。只有当酵母细胞在存在谷胱甘肽或其衍生物（如氧化型谷胱甘肽和γ-L-谷氨酰-L-半胱氨酸）的情况下于SPO培养基中培养时，酵母的孢子形成缺陷才能得到恢复。得出的结论是，谷胱甘肽是酿酒酵母进入减数分裂和/或孢子形成过程所必需的。
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