Sánchez Valiente S, Mostacero E, del Río A, Morales F
Servicio de Neurología, Hospital Clínico Universitario de Zaragoza.
Neurologia. 1994 Oct;9(8):337-41.
Given evidence that ischemic heart disease is the most frequent cause of death in patients with cerebrovascular disease, we used ergometrics to screen 80 patients with TIA for silent myocardial ischemia (SMI) at the neurological unit of Hospital Clínico Universitario in Zaragoza, Spain. The patients were compared with a control group of 80 with no signs of heart disease. Neither the patients nor the controls had ever shown clinical signs of coronary ischemia and their baseline electrocardiograms were normal. Stress test results were positive in 25 (31%) of the TIA patients, and in 4 (5%) (p < 0.001) of the controls, showing that the prevalence of SMI is significantly higher in TIA patients than in the general population. Hiperlipidemia (75% testing positive versus 43% negative, p < 0.01) and diabetes (31% testing positive versus 13% negative, p < 0.01) were the risk factors statistically related with a positive stress test.
鉴于有证据表明缺血性心脏病是脑血管疾病患者最常见的死亡原因，我们在西班牙萨拉戈萨大学临床医院的神经科，采用运动试验对80例短暂性脑缺血发作（TIA）患者进行无症状心肌缺血（SMI）筛查。将这些患者与80例无心脏病迹象的对照组进行比较。患者和对照组均未曾出现过冠状动脉缺血的临床症状，且其基线心电图正常。运动试验结果显示，25例（31%）TIA患者呈阳性，4例（5%）对照组患者呈阳性（p<0.001），表明TIA患者中SMI的患病率显著高于普通人群。高脂血症（75%检测呈阳性，43%呈阴性，p<0.01）和糖尿病（31%检测呈阳性，13%呈阴性，p<0.01）是与运动试验阳性有统计学关联的危险因素。
