Okumura A, Hayakawa F, Kuno K, Natsume J, Watanabe K
Department of Pediatrics, Anjo Kosei Hospital.
No To Hattatsu. 1994 Nov;26(6):475-9.
Brain CT scan was performed at 40 weeks of conceptional age in 17 preterm infants with periventricular leukomalacia (PVL). The finding of periventricular low density was not useful in differentiating patients with PVL from normal infants, because this finding was seen in 40% of normal infants. The following findings were characteristic of PVL: (1) a marked low density area in centrum semiovale, (2) an irregular outline of ventricular wall, and (3) low density spots in periventricular white matter. The findings of ventricular dilation with irregular wall and marked low density area in centrum semiovale were correlated with a finding of volume loss on MRI during late infancy and the severity of neurological impairment, especially in severely affected patients. Marked low density area in centrum semiovale was characteristic of severe PVL demonstrated on brain CT scan.
对17例患有脑室周围白质软化症（PVL）的早产儿在孕40周时进行了脑部CT扫描。脑室周围低密度的发现对于区分患有PVL的患者与正常婴儿并无帮助，因为在40%的正常婴儿中也可见到这一表现。以下表现是PVL的特征：（1）半卵圆中心有明显的低密度区；（2）心室壁轮廓不规则；（3）脑室周围白质中有低密度斑点。心室扩张伴壁不规则以及半卵圆中心有明显低密度区的表现与婴儿晚期MRI上的体积缩小以及神经功能损害的严重程度相关，尤其是在严重受累的患者中。半卵圆中心有明显低密度区是脑部CT扫描显示的重度PVL的特征。
