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斑马鱼脊髓运动神经元中的能量代谢

Energy metabolism in spinal motoneurons of the zebrafish.

作者信息

Van Raamsdonk W

机构信息

Department of Experimental Zoology, University of Amsterdam, The Netherlands.

出版信息

Eur J Morphol. 1994 Aug;32(2-4):212-6.

PMID:7803169
Abstract

Enzyme histochemical profiles of the energy metabolism in spinal motoneurons of fish, ranging in length from 18 mm to 53 mm, were investigated. Energy is used for ion pumps to maintain the resting membrane potential and for other processes of which transport and biosynthesis may be the most important. In this paper particular attention is paid to the impact of biosynthesis on the energy metabolism in motoneurons. As the innervation ratio of fish motoneurons increases dramatically during growth, we suppose that the formation and maintenance of functional connections with the target muscle accounts for the high level of the energy metabolism in motoneurons.

摘要

对体长从18毫米到53毫米的鱼类脊髓运动神经元能量代谢的酶组织化学特征进行了研究。能量用于离子泵以维持静息膜电位以及用于其他过程,其中运输和生物合成可能是最重要的。在本文中,特别关注生物合成对运动神经元能量代谢的影响。由于鱼类运动神经元的支配率在生长过程中急剧增加,我们推测与靶肌肉功能连接的形成和维持是运动神经元能量代谢水平高的原因。

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