Lee P A, Gareis F J
J Clin Endocrinol Metab. 1976 Jul;43(1):195-7. doi: 10.1210/jcem-43-1-195.
Luteinizing hormone-releasing hormone (100 mug iv) produced a response of LH, FSH, testosterone, and estradiol in children with premature pubarche that was not different from that among normal prepubertal children. Hence, this study provides no evidence that hypothalamic-pituitary-gonadal maturation occurs with the onset of premature sexual hair.
促黄体生成素释放激素(静脉注射100微克)在阴毛早现儿童中引起的促黄体生成素、促卵泡生成素、睾酮和雌二醇反应与正常青春期前儿童无异。因此,本研究没有提供证据表明下丘脑-垂体-性腺成熟随着性毛早现而发生。