C组和G组链球菌溶血素O基因的克隆与测序
Cloning and sequencing the streptolysin O genes of group C and group G streptococci.
作者信息
Okumura K, Hara A, Tanaka T, Nishiguchi I, Minamide W, Igarashi H, Yutsudo T
机构信息
Shionogi Institute for Medical Science, Osaka, Japan.
出版信息
DNA Seq. 1994;4(5):325-8. doi: 10.3109/10425179409020859.
PMID:7803818
Abstract
On the basis of the known streptolysin O (SLO) genomic sequence of Streptococcus pyogenes group A, we identified the SLO genes in some strains of group C and group G streptococci by the polymerase chain reaction procedure (PCR). The entire open reading frame region of these genes was cloned and analyzed. Their nucleotide sequence data showed that the defined SLO genes in group C and group G are almost identical to that of group A.
摘要
基于已知的化脓性链球菌A组链球菌溶血素O（SLO）基因组序列，我们通过聚合酶链反应程序（PCR）在一些C组和G组链球菌菌株中鉴定出了SLO基因。克隆并分析了这些基因的整个开放阅读框区域。它们的核苷酸序列数据表明，C组和G组中确定的SLO基因与A组的几乎相同。
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