Uri J V
Department of Microbiology and Immunology, Philadelphia College of Osteopathic Medicine, PA.
Acta Microbiol Immunol Hung. 1994;41(2):215-9.
The well-characterized strain of Escherichia coli ATCC 25922 recommended and widely used as a control Gram-negative bacterium for various laboratory experiments, especially for antibiotic susceptibility assays, was found to be antagonistic against another E. coli strain which is uniquely susceptible to fusidic acid, an antibiotic mainly active against Gram-positive bacteria. This antagonistic property appears to be selective, since it was not found against other E. coli or Staphylococcus aureus strains.
作为各种实验室实验(尤其是抗生素敏感性测定)的对照革兰氏阴性菌而被推荐并广泛使用的特征明确的大肠杆菌菌株ATCC 25922,被发现对另一种对夫西地酸(一种主要对革兰氏阳性菌有活性的抗生素)独特敏感的大肠杆菌菌株具有拮抗作用。这种拮抗特性似乎具有选择性,因为未发现它对其他大肠杆菌或金黄色葡萄球菌菌株有拮抗作用。